Friday, May 24, 2019

Common Tumor markers and cancer antigens mnemonics

Tumor Markers

CEA - C  olorectal Cancer (not exclusive)
PSA - P   rostate Cancer


Cancer Antigens

Breast CA


Pancreatic CA


Ovarian CA

Bone remodelling mnemonics

Osteoblasts - builds
Osteoclasts - cuts

Inflammatory Bowel Disease mnemonic



Crohn's Disease


C for Cobblestones

Cushing Syndrome simplified mnemonic

Cushing Syndrome (Simplified version)

Central obesity/Cortisol
Urinary free corisol
Suppressed immunity
Hypertension/ Hirsutism
Iatrogenic (Increased administration of corticosteroids)
Neoplasms
Glucose intolerance/Growth retardation

Carcinoid syndrome mnemonics

CARCinoid Syndrome
CARC

Cutaneous flushing
Asthmatic wheezing
Right sided valvular heart lesions
Cramping and diarrhea


Thursday, May 23, 2019

Cephalosporin coverage Mnemonic, Anaerobes



1st Gen
Gram (+) cocci

  • Staph, Strep
Gram (-) rods
  • PEcK 
  • P-roteus, E - coli, K -lebsiella pneumoniae
2nd GenGram (+) cocci

  • Staph, Strep
Gram (-) rods
  • HENPEcK 
  • H - Influenzae, E - nterobacter aerogenes
  • N - eisseria gonorrhea
  • P-roteus, E - coli, K -lebsiella pneumoniae

3rd Gen
Gram (+) cocci

  • Strep
Gram (-) rods
  • HENPEcK + P*
  • H - Influenzae, E - nterobacter aerogenes
  • N - eisseria gonorrhea
  • P-roteus, E - coli, K -lebsiella pneumoniae
  • P - seudomonas aureginosa (For some 3rd Gen)



Content: 4 ๐Ÿ…๐Ÿ…๐Ÿ…๐Ÿ… (Must-know)
Ease of memorisation: Very poor, requires repeated memorisation

Source: Lippincott

ABC of Anaerobes
Common Anaerobes

A - Actinomyces
B - Bacteroides Fragilis
C - Clostrodium sp.






Additional Notes:

3rd Gen cephalosporins: increased spectrum of activity against gram-negative bacteria, moderate activity against anaerobic bacteria, and reduced anti-gram-positive activity as compared with earlier cephalosporins

Cefoxitin 
Indication: Surgical Prophylaxis

Cefoxitin was the most active against 33 isolates of Bacteroides fragilis

Citations
Tally, F. P., Jacobus, N. V., Bartlett, J. G., & Gorbach, S. L. (1975). Susceptibility of anaerobes to cefoxitin and other cephalosporins. Antimicrobial agents and chemotherapy7(2), 128–132. doi:10.1128/aac.7.2.128

Congenital Heart Disease Chest x-ray Findings

Congenital Heart Disease Chest x-ray Findings

TOF: Boot-shaped Heart
TGA: Egg-shaped
TAPV: Snowman's sign
Truncus Arteriosus: Right-sided Aortic Arch
Ebstein Anomaly: Box-shaped Heart





Content: ๐Ÿ…๐Ÿ…๐Ÿ… High-yield
Ease of memorisation: poor

Congenital Cyanotic Heart Disease Mnemonic

Congenital Cyanotic Heart Disease   4T's 

T - etralogy of Fallot
T - runcus Arteriosus
T -ransposition of the Great vessels
T - Tricuspid Atresia

Tips: Associate "T" with Cyanotic; Tips of Toes/Fingers are Tinged-Blue  


Tetralogy of Fallot
P -ulmonary Stenosis
R-ight ventricular hypertrophy
O-verriding aorta
V-entricular Septal Defect
e


Tips: TOF is the most common CHD, it does not need to PROVe it. 
P - first means most significant; Pulmonary stenosis is the most significant component


Content: ๐Ÿ…๐Ÿ…๐Ÿ…๐Ÿ… Must-know
Ease: TF



https://www.pinterest.ph/pin/414471971927769172/?lp=true
https://images.app.goo.gl/XHJKZ3iB2qtxdw5W9









Rheumatic Fever Criteria Mnemonic

"JONES CAFE PAL"

Major Criteria
J -  joint Involvement
O - looks like a heart = Myocarditis
N - Nodules, subcutaneous
E - Erythema marginatum
S - Syndenham chorea


Minor Criteria
C - CRP increased
A - Arthralgia
F - Fever
E - elevated CSR

P - prolonged PR interval
A - anamnesis of Rheumatism
L - leukocytosis




Content: High-yield ๐Ÿ…๐Ÿ…๐Ÿ…
Ease of memorisation: Extremely difficult
Please give time to study this.


Source: Knowmedge

Scarlet Fever


S - orethroat
C - ircumoral Pallor
A - antecubital fossa, Petechiae --> Pastia lines
R - ash (Sandpaper)
L - ymphadenopathy
E - erythrogenic Toxin
T - ongue (Strawberry)




Content: High-yield๐Ÿ…๐Ÿ…๐Ÿ…
Ease of memorisation: ⭐⭐⭐



Source: https://www.medicowesome.com/2016/12/scarlet-fever-notes-and-mnemonic.html

Live Attenuated Vaccines Mnemonics











R - ubella
O - ral polio vaccine
M - easles
E - pidemic Typhus
I - nfluenza
M - umps
B -CG
P - lague
T - yphoid oral vaccine
Y -ellow fever



Content: Extremely Important: ๐Ÿ…๐Ÿ…๐Ÿ…๐Ÿ…
Ease of Memorisation: Extremely Difficult: 0

Epstein-Barr Virus Mnemonics

Epstein-Barr Virus

E
P
S
T
E
I - Infectious Mononucleosis
N - Nasopharyngeal Carcinoma

B - Burkitt's Lymphoma
A - Aids related Lymphoma (Hodgkins & Non-Hodgkins)
R
R




Content: ๐Ÿ…๐Ÿ… 
Ease of Memorisation: ⭐⭐


Congenital Rubella Mnemonics

ABCDE  FGHIJKLM of Congenital Rubella

A - Autism/Auditory defects
B - Blueberry muffin spots
C - Cardiac defects (PDA)
E  - Eye problems (Cataracts, Corneal Opacity)


F 
G - Growth Retardation
H - Hepatosplenomegaly
I - IUGR
J - Jaundice
K
L - Low platelets
M - Mental/Motor Retardation/IgM
N  - Neurologic
O  - Opthalmic
P - PDA


Content: High-yield ๐Ÿ…๐Ÿ…๐Ÿ…
Ease of Memorization:⭐⭐


Some days as an intern, I just woke up in the evening after a night duty listening to flightless bird while waters drenches my face on the shower, tired, contemplating of a lof things about my backlogs in the hospital and my review but also, especially about whether all the sacrifices is worth it.

But some days, I just smile because of a hot mug of coffee to push me thru the day.

Tuesday, May 21, 2019

Aminoglycosides

Aminoglycosides: common characteristics

AMINO:


A- Active Against Aerobic gram negative

M- Mechanism of resistance are Modifying enzymes

I– Inhibit protein synthesis by binding to 30S subunit

N- Nephrotoxic

O- Ototoxic













Sulfonamides

Sulfonamides: common characteristics SULFA:


S-Steven-Johnson syndrome

U-Urine precipitation/ Useful for UTI

L-Large spectrum

F-Folic acids synthesis blocker

A-Analog of PABA




Content:๐Ÿ…๐Ÿ…๐Ÿ…(High-yield)
Ease: ⭐⭐⭐⭐⭐

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